: Treatment Protocol for Pruritis in ESRD
Renal Palliative Care Initiative: Treatment Protocol for Pruritis in ESRD
This treatment protocol was created to address and manage occurrence of pruritis
in patients with end stage renal disease.
Clinical Care Tools - Symptom Management
Renal Palliative Care Initiative
Baystate Medical Center
759 Chestnut Street S2669
Springfield, MA 01199
Michael Germain, M.D.
How the grantee used this instrument:
This protocol was made available at the clinics and renal unit nursing stations.
esrd, end stage renal disease, pruritis, dialysis, kidney disease, symptom assessment
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- Mettang, T, Fritz, P, Weber, J, et al. "Uremic prutitius in patgients
on heomdialysis or continuous ambulatory peritoneal dialysis: The role of
plasma histamine and skin mast cells." Clinical Nephrology, 1990;
CL, Katz, AI, Wilson, RE, Merrill, JP. "Disappearance of uremic itrching
after subtotal parathyroidectomy." New England Journal of Medicine, 1968;
- Cawley, IP, Hoch-Ligeti,
C, Bond, GM. "The eccrine sweat glands of patients in uremia." Arch
Dermatol, 1961; 84:51.
- Massry, SG, Popovtzer, MM, Coburn, Jw, et al. "Intractable
pruritus as a manifestation of secondary hyperparathyroidism in uremia."
New England Journal of Medicine, 1968; 279:697.
- Parfitt, AM, Massry, SG, Winfield, AC, et al. "Disordered
calcium and phosphorus metabolism during maintenance hemodialysis." American
Journal of Medicine, 1971; 51:319.
- Blachley, JD, Blankenship, M, Menter, A, ET AL. "Uremic prutitus:
Skin divalent ion content and response to ultraviolet therapy." American
Kidney Diseases, 1985; 5:237.
- Hiroshige, K, Kabashima, N, Takasugi, M, Kuroiwa, A. "Optimal
dialysis improves uremic pruritis." American Journal of Kidney Diseases, 1995; 25:413.
- De Marchi,
S, Ceddhin, E, Villaltgra, D, et al. "Relief of pruritis and decreases in
plasma histamine concentrations during erythropoietin therapy
with uremia." New England Journal of Medicine, 1992; 326:969.
- Kessler, M, Moneret-Vautrin, DA,
Cao-Huu, T, et al. "Dialysis pruritis and sensitization." Nephron, 1992; 12:330.
K, & Mueller, B. "Uremic pruritis." American Journal of
Health-System Pharmacy, 1996; 53:2159.
- Peer, G, Kivity, S, Agami, O, et al. "Randomised crossover
trial of naltrexone in uraemic pruritis." Lancet, 1996;348: 1552.
S.R.B., Vianna,P.C.F, Lagon, N.V., et al. "Thalidomide for the Treatment
of Uremic Pruritis: A Crossover Randomized Double-Blind Trail."
- Tarng, DC, et al. "Hemodialysis-related pruritis:
a double-blind, placebo-controlled, crossover study of capsaicin 0.025% cream."
Nephron, 1996; 72:617.
- Balaskas, E, Bamihas, G, Karamouzis, M, et al. "Histamine
and serotonin in uremic pruritis: effect of ondansetron in CAPD-pruritic
- Francos, G, Kauh, V, Grittlen, S, "Elevated plasma histamine in
chronic uremia: effects of ketotifen on prutitus." International Journal
of Dermatology, 1991; 30:884.
D, Ianina, A, Reisin, E, "Cholestryramine in uraemic pruritis." British
Medical Journal, 1997; 1:752.
- Giovanetti, S, Barsotti, G, Cupisti, A, "Oral activated charcoal
inpataients with uremic pruritis." Nephron, 1995; 70:193.
- Schultz, B, & Roenigk,
K, "Uremic pruritus treated with ultraviolet light." Journal
of the American Medical Association, 1980; 243:1836.
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Posted April 2004
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Promoting Excellence in End-of-Life Care was a national program of the Robert Wood Johnson Foundation dedicated to long-term changes in health care institutions to substantially improve care for dying people and their families. Visit PromotingExcellence.org for more resources.